Indigenous Knowledge (IK) research has been dominated by methodologies and paradigms which tended to marginalize indigenous methods and ways of knowing as inferior. Social scientists have often failed to acknowledge the role and contribution of IK holders / practitioners in the development of holistic and integrated research methodologies. Mainstream institutions including academia and research need to redefine the new path based on the generation of new knowledge which can overcome the shortcomings of marginalization of indigenous methodologies and epistemology. The objective of this paper is therefore, to elaborate on the fundamental role and contribution of IK holders / practitioners in developing an all inclusive research methodology which will lead to the harnessing of knowledge for development. In the final analysis, this paper shall, therefore, adhere that the successful bridging of the gap between indigenous and mainstream research methodologies on IKS will depend on the accreditation and certification of IK holders and practitioners as organic and grassroots intellectuals.