Over the past few years interest in mixed-methods research in organization studies has grown rapidly. Yet the issue of rigor and relevance in this respect has received little attention. Rigor and relevance are two interrelated aspects of a scientific research which respectively represent theoretical and practical significance of the study. Hence they are critical dimensions of research design and conduct both in applied sciences such as social science and multidisciplinary fields such as organizational study. Although debate on these aspects in qualitative and quantitative research has received remarkable attention but the mixed-methods approach seems to be relatively underemphasized or at best being addressed inconclusively. Therefore, this essay aims to address this deficiency by incorporating methodological issues into mixed-methods approach from the perspective of organizational studies. The intention of this essay is to address the question of ‘how can studies applying mixed-methods design be seen rigorous and relevant?’ To this end, instances from exemplary research will be illustrated and discussed. Subsequently an integrative methodological approach in the form of a practical framework will be presented.